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01 February 2008

Rare Epilepsy Shines New Light on Glucose and the Brain (The Dana Foundation Website - 1 February 2008)

DanaAn article about how glucose accumulation in neurons is at the root of a rare form of epilepsy called Lafora disease appears on the Dana Foundation website.


Researchers in Spain studying a rare form of epilepsy have discovered that the metabolic mechanisms that could give neurons energy may also play a role in neurodegenerative diseases.

Lafora disease is an extremely rare and lethal type of genetic epilepsy that affects adolescents. “It is quite devastating,” says Joan J. Guinovart, director of Barcelona’s Institute for Research in Biomedicine and a professor at the University of Barcelona. “Children are normal until they are about 10 years old and then they start having seizures. From there, the disease evolves very rapidly.” About 200 people currently have Lafora disease and most die from six to ten years after the first symptoms are observed...

(To read the rest of the article, please click here).


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